CATH Domain 3fliA00

Superfamily	Retinoid X Receptor
Functional Family	Bile acid receptor isoform 4

NR1H4_HUMAN

Homo sapiens

Bile acid receptor

PDB	3FLI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR). Flatt, B., Martin, R., Wang, T.L., Mahaney, P., Murphy, B., Gu, X.H., Foster, P., Li, J., Pircher, P., Petrowski, M., Schulman, I., Westin, S., Wrobel, J., Yan, G., Bischoff, E., Daige, C., Mohan, R. J.Med.Chem.