CATH Domain 3fahA04

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.365	Aldehyde Oxidoreductase; domain 4
	3.30.365.10	Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain

Domain Context

CATH Clusters

Superfamily	Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain
Functional Family

Enzyme Information

1.2.99.7

Aldehyde dehydrogenase (FAD-independent).

based on mapping to UniProt Q46509

An aldehyde + H(2)O + acceptor = a carboxylate + reduced acceptor.

UniProtKB Entries (1)

MOP_DESGI

Desulfovibrio gigas

Aldehyde oxidoreductase

PDB Structure

PDB	3FAH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Kinetic, structural, and EPR studies reveal that aldehyde oxidoreductase from Desulfovibrio gigas does not need a sulfido ligand for catalysis and give evidence for a direct Mo-C interaction in a biological system. Santos-Silva, T., Ferroni, F., Thapper, A., Marangon, J., Gonzalez, P.J., Rizzi, A.C., Moura, I., Moura, J.J., Romao, M.J., Brondino, C.D. J.Am.Chem.Soc.