1 keywords

CATH Domain 3f3sB02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.1040 N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Homologous Superfamily 1.10.1040.10 N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2

Domain Context

CATH Clusters

Superfamily N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Functional Family lambda-crystallin homolog

Enzyme Information

1.1.1.45
L-gulonate 3-dehydrogenase.
based on mapping to UniProt Q9Y2S2
L-gulonate + NAD(+) = 3-dehydro-L-gulonate + NADH.
-!- Also oxidizes other L-3-hydroxyacids.

UniProtKB Entries (1)

Q9Y2S2
CRYL1_HUMAN
Homo sapiens
Lambda-crystallin homolog

PDB Structure

PDB 3F3S
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Crystal Structure of Human Lambda-Crystallin, CRYL1
Ugochukwu, E., Johansson, C., Yue, W.W., Kochan, G., Pilka, E., Kramm, A., Pike, A.C.W., Filippakopoulos, P., von Delft, F., Oppermann, U.
To be Published