CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.20 | Alpha-Beta Barrel | |
3.20.20 | TIM Barrel | |
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
Superfamily | Aldolase class I |
Functional Family | Uridine monophosphate synthetase |
Enzyme Information
2.4.2.10 |
Orotate phosphoribosyltransferase.
based on mapping to UniProt P11172
Orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23.
|
4.1.1.23 |
Orotidine-5'-phosphate decarboxylase.
based on mapping to UniProt P11172
Orotidine 5'-phosphate = UMP + CO(2).
-!- The enzyme from higher eukaryotes is identical with EC 2.4.2.10.
|
UniProtKB Entries (1)
P11172 |
UMPS_HUMAN
Homo sapiens
Uridine 5'-monophosphate synthase
|
PDB Structure
PDB | 3EX2 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase
Chemistry
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