CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1000 | HAD superfamily/HAD-like |
Domain Context
CATH Clusters
| Superfamily | HAD superfamily/HAD-like |
| Functional Family | N-acylneuraminate cytidylyltransferase A |
Enzyme Information
| 2.7.7.43 |
N-acylneuraminate cytidylyltransferase.
based on mapping to UniProt Q99KK2
CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate.
-!- Acts on N-acetyl- and N-glycolyl- derivatives.
|
UniProtKB Entries (1)
| Q99KK2 |
NEUA_MOUSE
Mus musculus
N-acylneuraminate cytidylyltransferase
|
PDB Structure
| PDB | 3EWI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme.
J.Mol.Biol.
|