CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1330 | 60s Ribosomal Protein L30; Chain: A; |
|
3.30.1330.50 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
Domain Context
CATH Clusters
| Superfamily | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
| Functional Family | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
Enzyme Information
| 4.6.1.12 |
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
based on mapping to UniProt P62617
2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl- D-erythritol 2,4-cyclodiphosphate + CMP.
-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.
|
UniProtKB Entries (1)
| P62617 |
ISPF_ECOLI
Escherichia coli K-12
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
|
PDB Structure
| PDB | 3ESJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy
J.Med.Chem.
|
