CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.70 | Complement Module; domain 1 |
|
2.10.70.10 | Complement Module, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Complement Module, domain 1 |
| Functional Family | Complement factor B |
Enzyme Information
| 3.4.21.43 |
Classical-complement-pathway C3/C5 convertase.
based on mapping to UniProt P06681
Selective cleavage of Arg-|-Ser bond in complement component C3 alpha- chain to form C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to form C5a and C5b.
-!- A complex of complement fragments C4b, C2a and C2b. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.21.44.
|
UniProtKB Entries (1)
| P06681 |
CO2_HUMAN
Homo sapiens
Complement C2
|
PDB Structure
| PDB | 3ERB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation
Acta Crystallogr.,Sect.D
|
