CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P05102
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

P05102
MTH1_HAEPH
Haemophilus parahaemolyticus
Modification methylase HhaI

PDB Structure

PDB 3EEO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
M. HhaI co-crystallized with synthetic dsDNA containing a propane diol in place of the deoxycytidine residue targeted for methylation.
Porta, J.C., Christman, J.K., Borgstahl, G.E.O.
To be Published