CATH Domain 3ea2A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.190	Phosphatidylinositol (PI) phosphodiesterase

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol (PI) phosphodiesterase
Functional Family	1-phosphatidylinositol phosphodiesterase

Enzyme Information

4.6.1.13

Phosphatidylinositol diacylglycerol-lyase.

based on mapping to UniProt P08954

1-phosphatidyl-1D-myo-inositol = 1D-myo-inositol 1,2-cyclic phosphate + 1,2-diacyl-sn-glycerol.

-!- This enzyme is bacterial. -!- Activity is also found in animals, but this activity is due to the presence of EC 3.1.4.11. -!- Formerly EC 3.1.4.10.

UniProtKB Entries (1)

P08954

PLC_BACTU

Bacillus thuringiensis

1-phosphatidylinositol phosphodiesterase

PDB Structure

PDB	3EA2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Modulation of bacillus thuringiensis phosphatidylinositol-specific phospholipase C activity by mutations in the putative dimerization interface. Shi, X., Shao, C., Zhang, X., Zambonelli, C., Redfield, A.G., Head, J.F., Seaton, B.A., Roberts, M.F. J.Biol.Chem.