CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Cationic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00760
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P00760
TRY1_BOVIN
Bos taurus
Cationic trypsin
Q7M1P4
Q7M1P4_SAGSA
Sagittaria sagittifolia
Serine proteinase inhibitor A

PDB Structure

PDB 3E8L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The ternary structure of double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation.
Bao, R., Zhou, C.Z., Jiang, C.-H., Lin, S.X., Chi, C.W., Chen, Y.X.
J.Biol.Chem.