CATH Domain 3e04A02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.200	Fumarase C; Chain A, domain 2
	1.20.200.10	Fumarase/aspartase (Central domain)

Domain Context

CATH Clusters

Superfamily	Fumarase/aspartase (Central domain)
Functional Family	Fumarate hydratase, mitochondrial

Enzyme Information

4.2.1.2

Fumarate hydratase.

based on mapping to UniProt P07954

(S)-malate = fumarate + H(2)O.

UniProtKB Entries (1)

FUMH_HUMAN

Homo sapiens

Fumarate hydratase, mitochondrial

PDB Structure

PDB	3E04
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of human fumarate hydratase Kavanagh, K.L., Picaud, S., Pilka, E.S., Yue, W.W., Roos, A.K., Filippakopoulos, P., von Delft, F., Arrowsmith, C.H., Wikstrom, M., Edwards, A.M., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC) TO BE PUBLISHED