CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.640 | Aspartate Aminotransferase; domain 2 | |
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Functional Family | tyrosine aminotransferase |
Enzyme Information
2.6.1.5 |
Tyrosine transaminase.
based on mapping to UniProt P17735
L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.
-!- L-phenylalanine can act instead of L-tyrosine. -!- The mitochondrial enzyme may be identical with EC 2.6.1.1. -!- The three isoenzymic forms are interconverted by EC 3.4.22.32 and EC 3.4.22.33. -!- The enzyme can also catalyze the final step in the methionine-salvage pathway of Klebsiella pneumoniae.
|
UniProtKB Entries (1)
P17735 |
ATTY_HUMAN
Homo sapiens
Tyrosine aminotransferase
|
PDB Structure
PDB | 3DYD |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Human Tyrosine Aminotransferase
To be Published
|