CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.630 | Cytochrome p450 |
|
1.10.630.10 | Cytochrome P450 |
Domain Context
CATH Clusters
| Superfamily | Cytochrome P450 |
| Functional Family | Allene oxide synthase, chloroplastic |
Enzyme Information
| 4.2.1.92 |
Hydroperoxide dehydratase.
based on mapping to UniProt Q96242
(9Z,11E,15Z)-(13S)-hydroperoxyoctadeca-9,11,15-trienoate = (9Z,15Z)- (13S)-12,13-epoxyoctadeca-9,11,15-trienoate + H(2)O.
-!- Acts on a number of unsaturated fatty-acid hydroperoxides, forming the corresponding allene oxides. -!- The product of the above reaction is unstable and is acted upon by EC 5.3.99.6 to form the cyclopentenone derivative (15Z)-12-oxophyto- 10,15-dienoate (OPDA), which is the first cyclic and biologically active metabolite in the jasmonate biosynthesis pathway.
|
UniProtKB Entries (1)
| Q96242 |
CP74A_ARATH
Arabidopsis thaliana
Allene oxide synthase, chloroplastic
|
PDB Structure
| PDB | 3DSJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes
Nature
|
