CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Shikimate dehydrogenase (NADP(+))

Enzyme Information

1.1.1.25
Shikimate dehydrogenase.
based on mapping to UniProt Q5HNV1
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.

UniProtKB Entries (1)

Q5HNV1
AROE_STAEQ
Staphylococcus epidermidis RP62A
Shikimate dehydrogenase (NADP(+))

PDB Structure

PDB 3DOO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray crystallographic and enzymatic analyses of shikimate dehydrogenase from Staphylococcus epidermidis
Han, C., Hu, T., Wu, D., Qu, S., Zhou, J., Ding, J., Shen, X., Qu, D., Jiang, H.
Febs J.