CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Formate--tetrahydrofolate ligase |
Enzyme Information
| 6.3.4.3 |
Formate--tetrahydrofolate ligase.
based on mapping to UniProt Q9X287
ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.
-!- In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity.
|
UniProtKB Entries (1)
| Q9X287 |
FTHS_THEMA
Thermotoga maritima MSB8
Formate--tetrahydrofolate ligase
|
PDB Structure
| PDB | 3DO6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of Putative Formyltetrahydrofolate Synthetase (TM1766) from THERMOTOGA MARITIMA at 1.85 A resolution
To be published
|
