CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.300 | GMP Synthetase; Chain A, domain 3 |
|
3.30.300.30 | ANL, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.300.30 |
| Functional Family | D-alanine--D-alanyl carrier protein ligase |
Enzyme Information
| 6.2.1.54 |
D-alanine--[D-alanyl-carrier protein] ligase.
based on mapping to UniProt Q81G39
ATP + D-alanine + holo-[D-alaninyl-carrier protein] = AMP + diphosphate + D-alanyl-[D-alanyl-carrier protein].
-!- The enzyme is involved in the modification of wall teichoic acids, as well as type I and IV lipoteichoic acids, with D-alanine residues. -!- It activates D-alanine using ATP to form a high-energy (D-alanyl)adenylate intermediate and subsequently transfers the alanyl moiety to the phosphopantheinyl prosthetic group of a D-alanyl-carrier protein (DltC).
|
UniProtKB Entries (1)
| Q81G39 |
DLTA_BACCR
Bacillus cereus ATCC 14579
D-alanine--D-alanyl carrier protein ligase
|
PDB Structure
| PDB | 3DHV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure and enantiomer selection by D-alanyl carrier protein ligase DltA from Bacillus cereus.
Biochemistry
|
