CATH Domain 3deaA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1820	alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily	alpha/beta hydrolase
Functional Family	Cutinase 1

Enzyme Information

3.1.1.74

Cutinase.

based on mapping to UniProt P11373

Cutin + H(2)O = cutin monomers.

-!- Cutin, a polymeric structural component of plant cuticles, is an hydroxy fatty acid polymer, usually C(16) or C(18) and that contains one to three hydroxyl groups. -!- The enzyme from several fungal sources also hydrolyzes the p-nitrophenyl esters of hexadecanoic acid. -!- It is however inactive toward several esters that are substrates for non-specific esterases.

UniProtKB Entries (1)

P11373

CUTI1_COLGL

Colletotrichum gloeosporioides

Cutinase 1

PDB Structure

PDB	3DEA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Catalysis by Glomerella cingulata Cutinase Requires Conformational Cycling between the Active and Inactive States of Its Catalytic Triad Nyon, M.P., Rice, D.W., Berrisford, J.M., Hounslow, A.M., Moir, A.J.G., Huang, H., Nathan, S., Mahadi, N.M., Bakar, F.D.A., Craven, C.J. J.Mol.Biol.