CATH Classification

Domain Context

CATH Clusters

Superfamily Ubiquitin activating enzymes (Uba3). Chain: B, domain 2
Functional Family NEDD8-activating enzyme E1 catalytic subunit

Enzyme Information

6.2.1.-
Acid--thiol ligases.
based on mapping to UniProt Q8TBC4

UniProtKB Entries (1)

Q13564
ULA1_HUMAN
Homo sapiens
NEDD8-activating enzyme E1 regulatory subunit

PDB Structure

PDB 3DBH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.
Souphron, J., Waddell, M.B., Paydar, A., Tokgoz-Gromley, Z., Roussel, M.F., Schulman, B.A.
Biochemistry