CATH Domain 3dbeA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.510	Transferase(Phosphotransferase); domain 1
	1.10.510.10	Transferase(Phosphotransferase) domain 1

Domain Context

CATH Clusters

Superfamily	Transferase(Phosphotransferase) domain 1
Functional Family	Serine/threonine-protein kinase PLK

Enzyme Information

UniProtKB Entries (1)

Q4KMI8_DANRE

Danio rerio

Serine/threonine-protein kinase PLK

PDB Structure

PDB	3DBE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors. Fucini, R.V., Hanan, E.J., Romanowski, M.J., Elling, R.A., Lew, W., Barr, K.J., Zhu, J., Yoburn, J.C., Liu, Y., Fahr, B.T., Fan, J., Lu, Y., Pham, P., Choong, I.C., VanderPorten, E.C., Bui, M., Purkey, H.E., Evanchik, M.J., Yang, W. Bioorg.Med.Chem.Lett.