CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.310 | TATA-Binding Protein |
|
3.30.310.20 | DNA-3-methyladenine glycosylase AlkA, N-terminal domain |
Domain Context
CATH Clusters
| Superfamily | DNA-3-methyladenine glycosylase AlkA, N-terminal domain |
| Functional Family | DNA-3-methyladenine glycosylase 2 |
Enzyme Information
| 3.2.2.21 |
DNA-3-methyladenine glycosylase II.
based on mapping to UniProt P04395
Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.
|
UniProtKB Entries (1)
| P04395 |
3MG2_ECOLI
Escherichia coli K-12
DNA-3-methyladenine glycosylase 2
|
PDB Structure
| PDB | 3D4V |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine.
J.Am.Chem.Soc.
|
