CATH Domain 3czoA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.275	Fumarase C; Chain B, domain 1
	1.10.275.10	Fumarase/aspartase (N-terminal domain)

Domain Context

CATH Clusters

Superfamily	Fumarase/aspartase (N-terminal domain)
Functional Family	Histidine ammonia-lyase

Enzyme Information

4.3.1.24

Phenylalanine ammonia-lyase.

based on mapping to UniProt Q3M5Z3

L-phenylalanine = trans-cinnamate + ammonia.

-!- Member of the aromatic amino acid lyase family, other members of which are EC 4.3.1.3 and EC 4.3.1.23 and EC 4.3.1.25. -!- The enzyme from some species is highly specific for phenylalanine. -!- Formerly EC 4.3.1.5.

UniProtKB Entries (1)

Q3M5Z3

PAL_ANAVT

Trichormus variabilis ATCC 29413

Phenylalanine ammonia-lyase

PDB Structure

PDB	3CZO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and biochemical characterization of the therapeutic Anabaena variabilis phenylalanine ammonia lyase. Wang, L., Gamez, A., Archer, H., Abola, E.E., Sarkissian, C.N., Fitzpatrick, P., Wendt, D., Zhang, Y., Vellard, M., Bliesath, J., Bell, S.M., Lemontt, J.F., Scriver, C.R., Stevens, R.C. J.Mol.Biol.