CATH Domain 3cwbV00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.210	Cytochrome Bc1 Complex; Chain I
	2.10.210.10	Cytochrome Bc1 Complex; Chain I

Domain Context

CATH Clusters

Superfamily	Cytochrome Bc1 Complex; Chain I
Functional Family

Enzyme Information

7.1.1.8

Quinol--cytochrome-c reductase.

based on mapping to UniProt Q5ZLR5

Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2).

-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and c(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC 1.6.99.3). -!- Formerly EC 1.10.2.2.

UniProtKB Entries (1)

Q5ZLR5

UCRI_CHICK

Gallus gallus

Cytochrome b-c1 complex subunit Rieske, mitochondrial

PDB Structure

PDB	3CWB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The role of molecular modeling in the design of analogues of the fungicidal natural products crocacins A and D. Crowley, P.J., Berry, E.A., Cromartie, T., Daldal, F., Godfrey, C.R., Lee, D.W., Phillips, J.E., Taylor, A., Viner, R. Bioorg.Med.Chem.