CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.50 | 3-Layer(bba) Sandwich |
|
3.50.50 | FAD/NAD(P)-binding domain |
|
3.50.50.60 | FAD/NAD(P)-binding domain |
Domain Context
CATH Clusters
| Superfamily | FAD/NAD(P)-binding domain |
| Functional Family |
Enzyme Information
| 1.14.13.218 |
5-methylphenazine-1-carboxylate 1-monooxygenase.
based on mapping to UniProt Q9HWG9
5-methylphenazine-1-carboxylate + NADH + O(2) = pyocyanine + NAD(+) + CO(2) + H(2)O.
-!- The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in the biosynthesis of pyocyanin, a toxin produced and secreted by the organism. -!- It can also act on phenazine-1-carboxylate, converting it into 1-hydroxyphenazine.
|
UniProtKB Entries (1)
| Q9HWG9 |
PHZS_PSEAE
Pseudomonas aeruginosa PAO1
5-methylphenazine-1-carboxylate 1-monooxygenase
|
PDB Structure
| PDB | 3C96 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa.
To be Published
|
