CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.10 | Ribonuclease H-like superfamily/Ribonuclease H |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease H-like superfamily/Ribonuclease H |
| Functional Family | Exodeoxyribonuclease I |
Enzyme Information
| 3.1.11.1 |
Exodeoxyribonuclease I.
based on mapping to UniProt P04995
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
-!- Preference for single-stranded DNA. -!- The Escherichia coli enzyme hydrolyzes glucosylated DNA. -!- Similar enzymes; mammalian DNase III, exonuclease IV, T2- and T4-induced exodeoxyribonucleases. -!- Formerly EC 3.1.4.25.
|
UniProtKB Entries (2)
| P04995 |
EX1_ECOLI
Escherichia coli K-12
Exodeoxyribonuclease I
|
| A0A0H3GL04 |
A0A0H3GL04_KLEPH
Klebsiella pneumoniae subsp. pneumoniae HS11286
Single-stranded DNA-binding protein
|
PDB Structure
| PDB | 3C94 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of Escherichia coli single-stranded DNA-binding protein stimulation of exonuclease I.
Proc.Natl.Acad.Sci.USA
|
