CATH Domain 3c49A01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.142	Poly(ADP-ribose) Polymerase; domain 1
	1.20.142.10	Poly(ADP-ribose) polymerase, regulatory domain

Domain Context

CATH Clusters

Superfamily	Poly(ADP-ribose) polymerase, regulatory domain
Functional Family	Poly [ADP-ribose] polymerase

Enzyme Information

2.4.2.-

Pentosyltransferases.

based on mapping to UniProt Q9Y6F1

UniProtKB Entries (1)

PARP3_HUMAN

Homo sapiens

Protein mono-ADP-ribosyltransferase PARP3

PDB Structure

PDB	3C49
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3. Lehtio, L., Jemth, A.S., Collins, R., Loseva, O., Johansson, A., Markova, N., Hammarstrom, M., Flores, A., Holmberg-Schiavone, L., Weigelt, J., Helleday, T., Schuler, H., Karlberg, T. J.Med.Chem.