CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | L-tryptophan--pyruvate aminotransferase 1 |
Enzyme Information
| 2.6.1.99 |
L-tryptophan--pyruvate aminotransferase.
based on mapping to UniProt Q9S7N2
L-tryptophan + pyruvate = indole-3-pyruvate + L-alanine.
-!- This plant enzyme, along with EC 1.14.13.168, is responsible for the biosynthesis of the plant hormone indole-3-acetate from L-tryptophan.
|
| 2.6.1.27 |
Tryptophan transaminase.
based on mapping to UniProt Q9S7N2
L-tryptophan + 2-oxoglutarate = (indol-3-yl)pyruvate + L-glutamate.
-!- Also acts on 5-hydroxytryptophan and, to a lesser extent, on the phenyl amino acids.
|
UniProtKB Entries (1)
| Q9S7N2 |
TAA1_ARATH
Arabidopsis thaliana
L-tryptophan--pyruvate aminotransferase 1
|
PDB Structure
| PDB | 3BWN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants
Cell(Cambridge,Mass.)
|
