CATH Domain 3bjiA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Vav guanine nucleotide exchange factor 2

Enzyme Information

UniProtKB Entries (1)

RAC1_HUMAN

Homo sapiens

Ras-related C3 botulinum toxin substrate 1

PDB Structure

PDB	3BJI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. Chrencik, J.E., Brooun, A., Zhang, H., Mathews, I.I., Hura, G.L., Foster, S.A., Perry, J.J., Streiff, M., Ramage, P., Widmer, H., Bokoch, G.M., Tainer, J.A., Weckbecker, G., Kuhn, P. J.Mol.Biol.