CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family | Chymotrypsinogen A |
Enzyme Information
| 3.4.21.1 |
Chymotrypsin.
based on mapping to UniProt P00766
Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.5 and EC 3.4.4.6.
|
UniProtKB Entries (2)
| P46443 |
GUAM_HIRNI
Hirudo nipponia
Guamerin
|
| P00767 |
CTRB_BOVIN
Bos taurus
Chymotrypsinogen B
|
PDB Structure
| PDB | 3BG4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The crystal structure of guamerin in complex with chymotrypsin and the development of an elastase-specific inhibitor.
J.Mol.Biol.
|
