CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Pyruvate carboxylase |
Enzyme Information
| 6.4.1.1 |
Pyruvate carboxylase.
based on mapping to UniProt P11498
ATP + pyruvate + HCO(3)(-) = ADP + phosphate + oxaloacetate.
-!- The animal enzyme requires acetyl-CoA.
|
UniProtKB Entries (1)
| P11498 |
PYC_HUMAN
Homo sapiens
Pyruvate carboxylase, mitochondrial
|
PDB Structure
| PDB | 3BG3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction.
Nat.Struct.Mol.Biol.
|
