CATH Domain 3bdzA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.630	Cytochrome p450
	1.10.630.10	Cytochrome P450

Domain Context

CATH Clusters

Superfamily	Cytochrome P450
Functional Family

Enzyme Information

1.14.14.133

1,8-cineole 2-endo-monooxygenase.

based on mapping to UniProt Q8VQF6

1,8-cineole + [reduced flavodoxin] + O(2) = 2-endo-hydroxy-1,8-cineole + [oxidized flavodoxin] + H(2)O.

-!- A cytochrome P450 (heme-thiolate) protein that uses a flavodoxin-like redox partner to reduce the heme iron. -!- Isolated from the bacterium Citrobacter braakii, which can use 1,8- cineole as the sole source of carbon. -!- Formerly EC 1.14.13.156.

UniProtKB Entries (1)

Q8VQF6

CINA_CITBR

Citrobacter braakii

1,8-cineole 2-endo-monooxygenase

PDB Structure

PDB	3BDZ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The critical role of substrate-protein hydrogen bonding in the control of regioselective hydroxylation in p450cin Meharenna, Y.T., Slessor, K.E., Cavaignac, S.M., Poulos, T.L., De Voss, J.J. J.Biol.Chem.