CATH Classification
Level | CATH Code | Description |
---|---|---|
![]() |
1 | Mainly Alpha |
![]() |
1.20 | Up-down Bundle |
![]() |
1.20.1110 | Calcium-transporting ATPase, transmembrane domain |
![]() |
1.20.1110.10 | Calcium-transporting ATPase, transmembrane domain |
Domain Context
CATH Clusters
Superfamily | Calcium-transporting ATPase, transmembrane domain |
Functional Family | Sodium/potassium-transporting ATPase subunit alpha-1 |
Enzyme Information
7.2.2.13 |
Na(+)/K(+)-exchanging ATPase.
based on mapping to UniProt P05024
ATP + H(2)O + Na(+)(Side 1) + K(+)(Side 2) = ADP + phosphate + Na(+)(Side 2) + K(+)(Side 1).
-!- P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- An enzyme from the plasma membrane of animal cells that catalyzes the efflux of three Na(+) and influx of two K(+) per ATP hydrolyzed. -!- It is involved in generating the plasma membrane electrical potential. -!- Formerly EC 3.6.1.37 and EC 3.6.3.9.
|
UniProtKB Entries (1)
P05024 |
AT1A1_PIG
Sus scrofa
Sodium/potassium-transporting ATPase subunit alpha-1
|
PDB Structure
PDB | 3B8E |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of the sodium-potassium pump.
Nature
|