CATH Domain 3aklA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1070	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5
	1.10.1070.20

Domain Context

CATH Clusters

Superfamily	1.10.1070.20
Functional Family	Serine/threonine-protein kinase CtkA

Enzyme Information

2.7.11.1

Non-specific serine/threonine protein kinase.

based on mapping to UniProt Q9ZKJ5

ATP + a protein = ADP + a phosphoprotein.

-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q9ZKJ5

CTKA_HELPJ

Helicobacter pylori J99

Serine/threonine-protein kinase CtkA

PDB Structure

PDB	3AKL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Helicobacter pylori proinflammatory protein up-regulates NF-kappaB as a cell-translocating Ser/Thr kinase Kim, D.J., Park, K.-S., Kim, J.-H., Yang, S.-H., Yoon, J.Y., Han, B.-G., Kim, H.S., Lee, S.J., Jang, J.Y., Kim, K.H., Kim, M.J., Song, J.-S., Kim, H.-J., Park, C.-M., Lee, S.-K., Lee, B.I., Suh, S.W. Proc.Natl.Acad.Sci.USA