CATH Classification

Domain Context

CATH Clusters

Superfamily Jelly Rolls
Functional Family

Enzyme Information

1.13.11.24
Quercetin 2,3-dioxygenase.
based on mapping to UniProt O00625
Quercetin + O(2) = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H(+).
-!- Quercetin is a flavonol (5,7,3',4'-tetrahydroxyflavonol).

UniProtKB Entries (1)

O00625
PIR_HUMAN
Homo sapiens
Pirin

PDB Structure

PDB 3ACL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A small-molecule inhibitor shows that pirin regulates migration of melanoma cells
Miyazaki, I., Simizu, S., Okumura, H., Takagi, S., Osada, H.
Nat.Chem.Biol.
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