CATH Domain 3aawC01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1160	Carbamate kinase
	3.40.1160.10	Acetylglutamate kinase-like

Domain Context

CATH Clusters

Superfamily	Acetylglutamate kinase-like
Functional Family	Aspartokinase

Enzyme Information

2.7.2.4

Aspartate kinase.

based on mapping to UniProt P26512

ATP + L-aspartate = ADP + 4-phospho-L-aspartate.

-!- The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 1.1.1.3. -!- This is also the case for two of the four isoenzymes in Arabidopsis thaliana. -!- The equilibrium constant strongly favors the reaction from right to left, i.e. the non-physiological direction of reaction.

UniProtKB Entries (2)

P26512	AK_CORGL Corynebacterium glutamicum ATCC 13032 Aspartokinase
Q93C54	Q93C54_CORCT Corynebacterium crenatum Aspartokinase LysC beta subunit

PDB Structure

PDB	3AAW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum Yoshida, A., Tomita, T., Kuzuyama, T., Nishiyama, M. J.Biol.Chem.