CATH Domain 3a8lB02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.30	SH3 type barrels.
	2.30.30.50

Domain Context

CATH Clusters

Superfamily	2.30.30.50
Functional Family

Enzyme Information

4.2.1.84

Nitrile hydratase.

based on mapping to UniProt P13449

An aliphatic amide = a nitrile + H(2)O.

-!- Acts on short-chain aliphatic nitriles, converting them into the corresponding acid amides. -!- Does not act on these amides or on aromatic nitriles (cf. EC 3.5.5.1).

UniProtKB Entries (1)

P13448

NHAA_RHOER

Rhodococcus erythropolis

Nitrile hydratase subunit alpha

PDB Structure

PDB	3A8L
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Kinetic and structural studies on roles of the serine ligand and a strictly conserved tyrosine residue in nitrile hydratase Yamanaka, Y., Hashimoto, K., Ohtaki, A., Noguchi, K., Yohda, M., Odaka, M. J.Biol.Inorg.Chem.