CATH Domain 2zy1A00

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.600	Farnesyl Diphosphate Synthase
	1.10.600.10	Farnesyl Diphosphate Synthase

Superfamily	Farnesyl Diphosphate Synthase
Functional Family	Dehydrosqualene synthase

2.5.1.96

4,4'-diapophytoene synthase.

based on mapping to UniProt A9JQL9

2 (2E,6E)-farnesyl diphosphate = 15-cis-4,4'-diapophytoene + 2 diphosphate.

-!- Typical of Staphylococcus aureus and some other bacteria such as Heliobacillus sp.

CRTM_STAAU

Staphylococcus aureus

4,4'-diapophytoene synthase

PDB	2ZY1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. Song, Y., Liu, C.I., Lin, F.Y., No, J.H., Hensler, M., Liu, Y.L., Jeng, W.Y., Low, J., Liu, G.Y., Nizet, V., Wang, A.H.J., Oldfield, E. J.Med.Chem.