CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.2010 | Zincin-like |
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3.30.2010.30 |
Domain Context
CATH Clusters
Superfamily | 3.30.2010.30 |
Functional Family | Putative aminopeptidase N |
Enzyme Information
3.4.11.2 |
Membrane alanyl aminopeptidase.
based on mapping to UniProt P04825
Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
-!- Is not activated by heavy metal ions. -!- Belongs to peptidase family M1. -!- Formerly EC 3.4.1.2, EC 3.4.3.5 and EC 3.4.13.6.
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UniProtKB Entries (1)
P04825 |
AMPN_ECOLI
Escherichia coli K-12
Aminopeptidase N
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PDB Structure
PDB | 2ZXG |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250
Acta Crystallogr.,Sect.D
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