CATH Classification

Domain Context

CATH Clusters

Superfamily Farnesyl Diphosphate Synthase
Functional Family Dehydrosqualene synthase

Enzyme Information

2.5.1.96
4,4'-diapophytoene synthase.
based on mapping to UniProt A9JQL9
2 (2E,6E)-farnesyl diphosphate = 15-cis-4,4'-diapophytoene + 2 diphosphate.
-!- Typical of Staphylococcus aureus and some other bacteria such as Heliobacillus sp.

UniProtKB Entries (1)

A9JQL9
CRTM_STAAU
Staphylococcus aureus
4,4'-diapophytoene synthase

PDB Structure

PDB 2ZCO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence.
Liu, C.I., Liu, G.Y., Song, Y., Yin, F., Hensler, M.E., Jeng, W.Y., Nizet, V., Wang, A.H., Oldfield, E.
Science
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