CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family | Prostate-specific antigen |
Enzyme Information
| 3.4.21.77 |
Semenogelase.
based on mapping to UniProt P07288
Preferential cleavage: -Tyr-|-Xaa-.
-!- Slowly inhibited by alpha-1-antichymotrypsin. -!- Belongs to peptidase family S1.
|
UniProtKB Entries (1)
| P07288 |
KLK3_HUMAN
Homo sapiens
Prostate-specific antigen
|
PDB Structure
| PDB | 2ZCL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody
J.Mol.Biol.
|
