CATH Domain 2zcfA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.330	Nitrile Hydratase; Chain A
	3.90.330.10	Nitrile hydratase alpha /Thiocyanate hydrolase gamma

Domain Context

CATH Clusters

Superfamily	Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Functional Family

Enzyme Information

4.2.1.84

Nitrile hydratase.

based on mapping to UniProt P13448

An aliphatic amide = a nitrile + H(2)O.

-!- Acts on short-chain aliphatic nitriles, converting them into the corresponding acid amides. -!- Does not act on these amides or on aromatic nitriles (cf. EC 3.5.5.1).

UniProtKB Entries (1)

P13449

NHAB_RHOER

Rhodococcus erythropolis

Nitrile hydratase subunit beta

PDB Structure

PDB	2ZCF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Mutational study on alphaGln90 of Fe-type nitrile hydratase from Rhodococcus sp. N771 Takarada, H., Kawano, Y., Hashimoto, K., Nakayama, H., Ueda, S., Yohda, M., Kamiya, N., Dohmae, N., Maeda, M., Odaka, M. Biosci.Biotechnol.Biochem.