CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q15418
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q15418
KS6A1_HUMAN
Homo sapiens
Ribosomal protein S6 kinase alpha-1

PDB Structure

PDB 2Z7S
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors.
Ikuta, M., Kornienko, M., Byrne, N., Reid, J.C., Mizuarai, S., Kotani, H., Munshi, S.K.
Protein Sci.
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