CATH Domain 2yz3A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.15	Metallo-beta-lactamase; Chain A
	3.60.15.10	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

Domain Context

CATH Clusters

Superfamily	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family	Class B metallo-beta-lactamase

Enzyme Information

UniProtKB Entries (1)

Q7BJM5_PSEPU

Pseudomonas putida

Class B carbapenemase VIM-2

PDB Structure

PDB	2YZ3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystallographic investigation of the inhibition mode of a VIM-2 metallo-beta-lactamase from Pseudomonas aeruginosa by a mercaptocarboxylate inhibitor. Yamaguchi, Y., Jin, W., Matsunaga, K., Ikemizu, S., Yamagata, Y., Wachino, J., Shibata, N., Arakawa, Y., Kurosaki, H. J.Med.Chem.