CATH Domain 2yt0A01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	amyloid beta A4 precursor protein-binding family B member 2

Enzyme Information

UniProtKB Entries (1)

APBB2_MOUSE

Mus musculus

Amyloid-beta A4 precursor protein-binding family B member 2

PDB Structure

PDB	2YT0
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode Li, H., Koshiba, S., Hayashi, F., Tochio, N., Tomizawa, T., Kasai, T., Yabuki, T., Motoda, Y., Harada, T., Watanabe, S., Inoue, M., Hayashizaki, Y., Tanaka, A., Kigawa, T., Yokoyama, S. J.Biol.Chem.