CATH Domain 2yiiA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.200	Fumarase C; Chain A, domain 2
	1.20.200.10	Fumarase/aspartase (Central domain)

Domain Context

CATH Clusters

Superfamily	Fumarase/aspartase (Central domain)
Functional Family

Enzyme Information

4.3.1.24	Phenylalanine ammonia-lyase. based on mapping to UniProt Q68G84 L-phenylalanine = trans-cinnamate + ammonia. -!- Member of the aromatic amino acid lyase family, other members of which are EC 4.3.1.3 and EC 4.3.1.23 and EC 4.3.1.25. -!- The enzyme from some species is highly specific for phenylalanine. -!- Formerly EC 4.3.1.5.
5.4.3.10	Phenylalanine aminomutase (L-beta-phenylalanine forming). based on mapping to UniProt Q68G84 L-phenylalanine = L-beta-phenylalanine. -!- Cf. EC 5.4.3.11.

UniProtKB Entries (1)

PAM_TAXWC

Taxus chinensis

Phenylalanine aminomutase (L-beta-phenylalanine forming)

PDB Structure

PDB	2YII
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mechanism-Inspired Engineering of Phenylalanine Aminomutase for Enhanced Beta-Regioselective Asymmetric Amination of Cinnamates. Wu, B., Szymanski, W., Wybenga, G.G., Heberling, M.M., Bartsch, S., De Wildeman, S., Poelarends, G.J., Feringa, B.L., Dijkstra, B.W., Janssen, D.B. Angew.Chem.Int.Ed.Engl.