CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.150.650
Functional Family 3',5'-nucleoside bisphosphate phosphatase

Enzyme Information

3.1.3.97
3',5'-nucleoside bisphosphate phosphatase.
based on mapping to UniProt Q7NXD4
Nucleoside 3',5'-bisphosphate + H(2)O = nucleoside 5'-phosphate + phosphate.
-!- The enzyme, characterized from the bacterium Chromobacterium violaceum, has similar catalytic efficiencies with all the bases. -!- The enzyme has similar activity with ribonucleoside and 2'-deoxyribonucleoside 3',5'-bisphosphates, but shows no activity with nucleoside 2',5'-bisphosphates (cf. EC 3.1.3.7).

UniProtKB Entries (1)

Q7NXD4
35NBP_CHRVO
Chromobacterium violaceum ATCC 12472
3',5'-nucleoside bisphosphate phosphatase

PDB Structure

PDB 2YB4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Prospecting for Unannotated Enzymes: Discovery of a 3',5'-Nucleotide Bisphosphate Phosphatase within the Amidohydrolase Superfamily.
Cummings, J.A., Vetting, M.W., Ghodge, S.V., Xu, C., Hillerich, B., Seidel, R.D., Almo, S.C., Raushel, F.M.
Biochemistry
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