CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.450 | Beta-Lactamase |
|
3.30.450.40 | GAF domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.450.40 |
| Functional Family | Oxygen sensor histidine kinase response regulator DevS/DosS |
Enzyme Information
| 2.7.13.3 |
Histidine kinase.
based on mapping to UniProt P9WGK3
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.
|
UniProtKB Entries (1)
| P9WGK3 |
DEVS_MYCTU
Mycobacterium tuberculosis H37Rv
Oxygen sensor histidine kinase response regulator DevS/DosS
|
PDB Structure
| PDB | 2Y79 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Blockage of the Channel to Heme by the E87 Side Chain in the Gaf Domain of Mycobacterium Tuberculosis Doss Confers the Unique Sensitivity of Doss to Oxygen.
FEBS Lett.
|
