CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.9100 | Dehydroquinase, class II |
Domain Context
CATH Clusters
| Superfamily | Dehydroquinase, class II |
| Functional Family | 3-dehydroquinate dehydratase |
Enzyme Information
| 4.2.1.10 |
3-dehydroquinate dehydratase.
based on mapping to UniProt P9WPX7
3-dehydroquinate = 3-dehydroshikimate + H(2)O.
|
UniProtKB Entries (1)
| P9WPX7 |
AROQ_MYCTU
Mycobacterium tuberculosis H37Rv
3-dehydroquinate dehydratase
|
PDB Structure
| PDB | 2Y77 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A prodrug approach for improving antituberculosis activity of potent Mycobacterium tuberculosis type II dehydroquinase inhibitors.
J. Med. Chem.
|