CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt O68720
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

O68720
O68720_YERPE
Yersinia pestis
Targeted effector protein

PDB Structure

PDB 2Y2F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia Pestis Outer Protein H (Yoph) Phosphatase.
Bahta, M., Lountos, G.T., Dyas, B., Kim, S., Ulrich, R.G., Waugh, D.S., Burke, T.R.
J.Med.Chem.