CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
Superfamily | NAD(P)-binding Rossmann-like Domain |
Functional Family | UDP-N-acetylmuramoylalanine--D-glutamate ligase |
Enzyme Information
6.3.2.9 |
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase.
based on mapping to UniProt P14900
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanine + D-glutamate = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate.
-!- Involved in the synthesis of a cell-wall peptide in bacteria.
|
UniProtKB Entries (1)
P14900 |
MURD_ECOLI
Escherichia coli K-12
UDP-N-acetylmuramoylalanine--D-glutamate ligase
|
PDB Structure
PDB | 2Y1O |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus.
ACS Med Chem Lett
|