CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.91 | Restriction Endonuclease |
|
3.40.91.60 |
Domain Context
CATH Clusters
| Superfamily | 3.40.91.60 |
| Functional Family | RNA-directed RNA polymerase L |
Enzyme Information
| 2.7.7.48 |
RNA-directed RNA polymerase.
based on mapping to UniProt A5HC98
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.
|
| 3.1.-.- |
Acting on ester bonds.
based on mapping to UniProt A5HC98
|
UniProtKB Entries (1)
| A5HC98 |
L_BUNLC
La Crosse virus
RNA-directed RNA polymerase L
|
PDB Structure
| PDB | 2XI7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription.
Plos Pathog.
|